Our HyFusn platform provides a robust approach for generating hybridomas using both conventional and enriched B-cell sources, delivering monoclonal antibodies with high specificity and affinity (pM).
Key Features of HyFusn Platform
- Fusion Techniques: PEG and electrofusion with proprietary Sp2/0 fusion partner
- Source Material: Spleen, lymph node, bone marrow B cells
- Target-specific B-cell enrichment before fusion
- Post-fusion sorting and optimized limiting dilution
- Turnaround Time (TAT): ~3 weeks
Screening Approaches
- ELISA, flow cytometry, Octet, and SPR
- Clone uniqueness verified through v-gene sequencing
- High-throughput screening via automation (Bravo, Multidrop, Clonepix)
Why Aurigene Hybridoma & Fusion Technologies?
Rapid hybridoma generation using advanced fusion methods
High-efficiency screening to reduced timelines
Targeted enrichment for high-quality hybridomas
Expertise in custom antibody formats and adjuvant strategies
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Hyderabad R and D Center
Bangalore R and D Center
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We understand that clear communication is essential to successful collaborations, and that's why we have a dedicated team that is always ready to help you. Whether you have questions about our services, want to discuss a potential partnership, or simply want to learn more about our company, we're here to help.
Our team of experts is dedicated to providing personalised solutions tailored to your unique needs. So, please don't hesitate to reach out to us. We look forward to hearing from you and helping you achieve your business goals.
Learning Resources
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Development and assessment of a Bcs class II - SGLT2 (Sodium Glucose Cotransporter 2) inhibitor drug in the form of solid lipid Nanoparticles by selecting different lipids, co-surfactants, and manufacturing techniques
Drug Delivery System (DDS) has been used successfully in the past few decades to cure illnesses and enhance health because of its improved systemic circulation and ability to regulate the drug's pharmacological action. As pharmacology and pharmacokinetics advanced, the idea of controlled release emerged, demonstrating the significance of drug release in assessing...
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Development of novel paullone-based PROTACs as anticancer agents
Proteolysis-targeting chimera (PROTACs) represents a promising modality that has gained significant attention for cancer treatment. Using PROTAC technology, we synthesized novel structurally modified paullone-based PROTACs using Cereblon (CRBN) and Von Hippel–Lindau (VHL) E3 ligands....
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Development and verification of RP-HPLC method for the quantitative determination of Decitabine in tablet dosage formulation
Decitabine is an anti-cancer chemotherapy drug. This article describes method development and method verification of Assay of Decitabine in tablet formulation. A new, precise, rapid, accurate RP-HPLC method has been developed for the estimation of Decitabine in pharmaceutical tablets dosage form. After optimization the good chromatographic separation was achieved...
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